Article

Factor XI localization in human deep venous thrombus and function of activated factor XI on venous thrombus formation and hemostasis in rabbit

2023-09-22

Abstract excerpt

<h4>Background</h4> Novel anticoagulants targeting coagulation factor XI (FXI)/activated FXI (FXIa) are under development. However, whether FXI is present in human deep vein thrombosis (DVT) and whether FXIa and activated factor X (FXa) play different roles in venous thrombus formation and hemostasis remain unclear. This study aimed to determine the presence of FXI in DVT and the effects of direct oral FXIa and F...

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Literature Corpus work: 193eff04-0189-5e4c-a434-97d1d0842492
DOI: 10.1101/2023.09.19.558346

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