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Pathogenic Genetic Variants From Highly Connected Cancer Susceptibility Genes Confer the Loss of Structural Stability

2021-05-05

Abstract excerpt

Genetic polymorphisms in DNA damage repair and tumor suppressor genes have been associated with increasing the risk of several types of cancer. Analyses of putative functional single nucleotide polymorphisms (SNP) in such genes can greatly improve human health by guiding choice of therapeutics. In this study, we selected nine genes responsible for various cancer types for gene enrichment analysis and found that BR...

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Literature Corpus work: 192fcbe5-5def-5dd5-ac8f-3afde3a763f8
DOI: 10.21203/rs.3.rs-480522/v1

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