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Article

Pathogenic genetic variants from highly connected cancer susceptibility genes confer the loss of structural stability.

Scientific reports - 28 Sept 2021

Reza Mahjerin Nasrin, Ferdous Nadim, Emon Md Tabassum Hossain, Islam Md Shariful, Mohiuddin A K M, Hossain Mohammad Uzzal

Abstract excerpt

Genetic polymorphisms in DNA damage repair and tumor suppressor genes have been associated with increasing the risk of several types of cancer. Analyses of putative functional single nucleotide polymorphisms (SNP) in such genes can greatly improve human health by guiding choice of therapeutics. In this study, we selected nine genes responsible for various cancer types for gene enrichment analysis and found that...

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Identifiers

PMID: 34584144
DOI: 10.1038/s41598-021-98547-y
PMCID: PMC8479081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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