Article

Genetic analysis of age-related macular degeneration highlights precision therapy opportunities for patients with high polygenic risk

2026-03-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Importance:</bold> In the past two decades, genetic studies have elucidated the contributions of key biological pathways to the pathogenesis of age-related macular degeneration (AMD), including the predominant role of complement. Yet, clinical treatment of AMD with complement inhibitors has met with limited success. <bold>Objectives:</bold> To examine whether genetic heteroge...

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Literature Corpus work: 1927ddab-278f-5144-b8dc-b2c330a718f9
DOI: 10.21203/rs.3.rs-8863554/v1

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