Article
Genetic studies of age-related macular degeneration: lessons, challenges, and opportunities for disease management.
Ophthalmology - 1 Dec 2012
Priya Rinki Ratna, Chew Emily Y, Swaroop Anand
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is a common cause of visual impairment in individuals >55 years of age worldwide. The varying clinical phenotypes of AMD result from contributions of genetic, epigenetic, and nongenetic (environmental) factors. Genetic studies of AMD have come of age as a direct result of tremendous gains from the human genome project, genome-wide association studies, and...
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