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Article

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.

Genome medicine - 27 Mar 2017

Grassmann Felix, Kiel Christina, Zimmermann Martina E, Gorski Mathias, Grassmann Veronika, Stark Klaus, Heid Iris M, Weber Bernhard H F

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance. So far, little is known about a genetic overlap between AMD and other complex diseases or disease-relevant traits. METHODS: For each of 60 complex diseases/traits with...

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Source

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Identifiers

PMID: 28347358
DOI: 10.1186/s13073-017-0418-0
PMCID: PMC5368911

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