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Article

Age-Related Macular Degeneration and Its Genetic Risk: A Population-based Study.

Current eye research - 1 Jan 2025

Garzone Davide, Imtiaz Mohammed Aslam, Mauschitz Matthias M, Aziz N Ahmad, Holz Frank G, Breteler Monique M B, Finger Robert P

Abstract excerpt

PURPOSE: Specific genetic factors might serve as markers for risk stratification of AMD progression, but their association with key features of AMD has not been fully elucidated. Thus, we investigated the association between overall and pathway-specific genetic risk scores (GRS) and lead loci (ARMS2, CFH) with AMD stages and features of high-risk nonlate AMD, including reticular pseudodrusen (RPD) and large...

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Identifiers

PMID: 39155542
DOI: 10.1080/02713683.2024.2388692

Genes

ARMS2
CFH

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