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Article

Genetic Aspects of Age-Related Macular Degeneration and Their Therapeutic Potential.

International journal of molecular sciences - 31 Oct 2022

Stradiotto Elisa, Allegrini Davide, Fossati Giovanni, Raimondi Raffaele, Sorrentino Tania, Tripepi Domenico, Barone Gianmaria, Inforzato Antonio, Romano Mario R

Abstract excerpt

Age-related macular degeneration (AMD) is a complex and multifactorial disease, resulting from the interaction of environmental and genetic factors. The continuous discovery of associations between genetic polymorphisms and AMD gives reason for the pivotal role attributed to the genetic component to its development. In that light, genetic tests and polygenic scores have been created to predict the risk of...

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Identifiers

PMID: 36362067
DOI: 10.3390/ijms232113280
PMCID: PMC9653831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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