Article

Microtubule-associated proteins promote microtubule generation in the absence of γ-tubulin in human colon cancer cells

2021-08-13

Abstract excerpt

γ-Tubulin complex acts as the predominant microtubule (MT) nucleator that initiates MT formation and is therefore an essential factor for cell proliferation. Nonetheless, cellular MTs are formed after experimental depletion of the γ-tubulin complex, suggesting that cells possess other factors that drive MT nucleation. Here, by combining gene knockout, auxin-inducible degron, RNA interference, MT depolymerisation/r...

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Literature Corpus work: 18f3fe1a-78ef-5134-8363-a7a516863d0c
DOI: 10.1101/2021.08.13.456214

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