Article

Circulating cell-free messenger RNA secretome characterization of primary sclerosing cholangitis

2022-08-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND & AIMS</h4> Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease characterized by multi-focal bile duct strictures. To date, underlying molecular mechanisms of PSC remain unclear and therapeutic options for PSC patients are limited. We performed cell-free messenger RNA (cf-mRNA) next generation sequencing (RNA-Seq) to characterize the circulating transcr...

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Literature Corpus work: 18f0e9ef-4edb-5eea-959f-4b10c91707a1
DOI: 10.1101/2022.08.22.22278964

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