Article

Phosphorylation of STIM1 at ERK/CDK sites is dispensable for cell migration and ER partitioning in mitosis

2021-07-06

Abstract excerpt

<h4>ABSTRACT</h4> Store-operated Ca 2+ entry (SOCE) is a ubiquitous Ca 2+ influx required for multiple physiological functions including cell motility. SOCE is activated in response to depletion of intracellular Ca 2+ stores following the activation of endoplasmic reticulum (ER) Ca 2+ sensor STIM1 which recruits the plasma membrane (PM) Ca 2+ channel Orai1 at ER-PM junctions to induce Ca 2+ influx. STIM1 is...

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Literature Corpus work: 18b3a3e1-47d4-5e1f-a437-8bbe9cc8a051
DOI: 10.1101/2021.07.06.451280

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