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Article

The expressed mutational landscape of microsatellite stable colorectal cancers.

Genome medicine - 1 Sept 2021

Sveen Anita, Johannessen Bjarne, Eilertsen Ina A, Røsok Bård I, Gulla Marie, Eide Peter W, Bruun Jarle, Kryeziu Kushtrim, Meza-Zepeda Leonardo A, Myklebost Ola, Bjørnbeth Bjørn A, Skotheim Rolf I, Nesbakken Arild, Lothe Ragnhild A

Abstract excerpt

BACKGROUND: Colorectal cancer is the 2nd leading cause of cancer-related deaths with few patients benefiting from biomarker-guided therapy. Mutation expression is essential for accurate interpretation of mutations as biomarkers, but surprisingly, little has been done to analyze somatic cancer mutations on the expression level. We report a large-scale analysis of allele-specific mutation expression. METHODS:...

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Identifiers

PMID: 34470667
DOI: 10.1186/s13073-021-00955-2
PMCID: PMC8411524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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