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180 GENETIC VARIATION ASSOCIATED WITH LOW-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS INFLUENCES ZFHX3 EXPRESSION

2013-05-01

Abstract excerpt

The ZFHX3 gene in chromosome 16q22 codes for a transcription factor which controls expression of platelet-derived growth factor receptor beta (PDGRB). Genome-wide association studies (GWAS) have identified several single-nucleotide polymorphisms (SNPs) in this region which are associated with cardiovascular disease phenotypes. rs2106261 and rs7193343 in intron 1 are associated withatrial fibrillation (AF), rs71993...

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Literature Corpus work: 1880b424-1c9c-5e6b-8e43-f58f11fc5f97
DOI: 10.1136/heartjnl-2013-304019.180

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