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Article

Genetic polymorphisms in ZFHX3 are associated with atrial fibrillation in a Chinese Han population.

PloS one - 1 Jan 2014

Liu Yaowu, Ni Bixian, Lin Yuan, Chen Xin-guang, Fang Zhen, Zhao Liyan, Hu Zhibin, Zhang Fengxiang

Abstract excerpt

BACKGROUND: The gene zinc finger homeobox 3 (ZFHX3) encodes a transcription factor with cardiac expression and its genetic variants are associated with atrial fibrillation (AF). We aimed to explore the associations between single nucleotide polymorphisms (SNPs) of ZFHX3 and the risk of AF in a Chinese Han population. METHODS: We genotyped eight SNPs, including seven potentially functional SNPs and one previously...

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Identifiers

PMID: 24983873
DOI: 10.1371/journal.pone.0101318
PMCID: PMC4077770

Genes

ZFHX3

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