Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct Features of Plasma Ultrashort Single-Stranded Cell-Free DNA as Biomarkers for Lung Cancer Detection

19 Sept 2023

Abstract excerpt

BACKGROUND: Using broad range cell-free DNA sequencing (BRcfDNA-Seq), a nontargeted next-generation sequencing (NGS) methodology, we previously identified a novel class of approximately 50 nt ultrashort single-stranded cell-free DNA (uscfDNA) in plasma that is distinctly different from 167 bp mononucleosomal cell-free DNA (mncfDNA). We hypothesize that uscfDNA possesses characteristics that are useful for disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37725931
DOI: 10.1093/clinchem/hvad131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct Features of Plasma Ultrashort Single-Stranded Cell-Free DNA as Biomarkers for Lung Cancer DetectionPMID 37725931Read ↗

Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNASemantic proximity Read ↗

Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNASemantic proximity Read ↗

Cell-free DNA end characteristics enable accurate and sensitive cancer diagnosisSemantic proximity Read ↗

Cell-Free DNA: Features and Attributes Shaping the Next Frontier in Liquid BiopsySemantic proximity Read ↗

Short single-stranded DNA with putative non-canonical structures comprises a novel class of plasma cell-free DNASemantic proximity Read ↗

Cell‐free DNA‐associated multi‐feature applications in cancer diagnosis and treatmentSemantic proximity Read ↗

Early Lung Cancer Detection Using Nucleotide Transition Probabilities in plasma cell-free DNASemantic proximity Read ↗

Exploring the Role of Circulating Cell-Free DNA in Disease Diagnosis and TherapySemantic proximity Read ↗

Detection and characterization of lung cancer using cell-free DNA fragmentomesSemantic proximity Read ↗

Cancer-like fragmentomic characteristics of somatic variants in cell-free DNASemantic proximity Read ↗

Cell-free DNA fragmentomics: a universal framework for early cancer detection and monitoringSemantic proximity Read ↗

Circulating extracellular vesicles in lung cancer patients are not enriched in tumor-derived DNA fragments as revealed by whole genome sequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.