Article
Cell-free DNA approaches for cancer early detection and interception.
Journal for immunotherapy of cancer - 1 Sept 2023
Medina Jamie E, Dracopoli Nicholas C, Bach Peter B, Lau Anna, Scharpf Robert B, Meijer Gerrit A, Andersen Claus Lindbjerg, Velculescu Victor E
Abstract excerpt
Rapid advancements in the area of early cancer detection have brought us closer to achieving the goals of finding cancer early enough to treat or cure it, while avoiding harms of overdiagnosis. We evaluate progress in the development of early cancer detection tests in the context of the current principles for cancer screening. We review cell-free DNA (cfDNA)-based approaches using mutations, methylation, or...
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