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MicroRNA-222 carried by plasma-derived exosomes as an earlier biomarker to alert the abnormal phosphorylation of Tau caused by shRNA-PCSK9 and its correlation with Aβ1-42Ab.

2023-01-12

Abstract excerpt

<title>Abstract</title> <p>The clinical adverse reaction monitoring data of Human subtilisin converting enzyme 9 gene (proprotein converting enzyme subtilisin/kexin type 9, PCSK9) inhibitors showed that there were neurocognitive adverse events. In order to early warning of the potential danger of PCSK9 inhibitors to cognitive impairment in the process of regulating lipid homeostasis, this study aimed to explore t...

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Literature Corpus work
187681bf-868f-575d-a438-41fb90321b2c
DOI
10.21203/rs.3.rs-2437137/v1
Open publication

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