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Dental pulp mesenchymal stem cell-derived exosomes inhibit neuroinflammation and microglial pyroptosis in subarachnoid hemorrhage via the miRNA-197-3p/Foxo3 axis

2024-01-23

Abstract excerpt

<title>Abstract</title> <p>Background Subarachnoid hemorrhage (SAH) is a severe stroke subtype that lacks effective treatment. Exosomes derived from human dental pulp stem cells (DPSCs) are a promising acellular therapeutic strategy for neurological diseases. However, the therapeutic effects of DPSC-derived exosomes (DPSC-Exos) on SAH remain unknown. In this study, we investigated the therapeutic effects and mec...

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Literature Corpus work
a1f5dd5a-7315-5b40-819f-53045b9ec88a
DOI
10.21203/rs.3.rs-3877856/v1
Open publication

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Dental pulp mesenchymal stem cell-derived exosomes inhibit neuroinflammation and microglial pyroptosis in subarachnoid hemorrhage via the miRNA-197-3p/Foxo3 axisDOI 10.21203/rs.3.rs-3877856/v1
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