Article

Region-specific alterations of perineuronal net expression in postmortem autism brain tissue

2022-01-02

Abstract excerpt

Genetic variance in ASD is often associated with mechanisms that broadly fall into the category of neuroplasticity. Parvalbumin positive neurons and their surrounding perineuronal nets (PNNs) are important factors in critical period plasticity and have both been implicated in ASD. PNNs are found in high density within output structures of the cerebellum and basal ganglia, two regions that are densely connected to...

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Literature Corpus work: 1875354f-d9ea-519b-8696-e5c6d9645752
DOI: 10.1101/2021.12.31.474655

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