Article

Spatial Transcriptomics Reveals the Temporal Architecture of the Seminiferous Epithelial Cycle and Precise Sertoli-Germ Synchronization

2024-10-31

Abstract excerpt

<h4>Summary</h4> Spermatogenesis is characterized by the seminiferous epithelial cycle, a periodic pattern of germ cell differentiation with a wave-like progression along the length of seminiferous tubules. While key signaling and metabolic components of the cycle are known, the transcriptional changes across the cycle and the correlations between germ cell and somatic lineages remain undefined. Here, we use spat...

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Literature Corpus work: 181469bf-fdc2-53be-96e3-80a115377c2b
DOI: 10.1101/2024.10.28.620681

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