Article

Deciphering cell lineage specification during male sex determination with single-cell RNA sequencing

2017-09-18

Abstract excerpt

<h4>Summary</h4> The gonad is a unique biological system for studying cell fate decisions. However, major questions remain regarding the identity of somatic progenitor cells and the transcriptional events driving cell differentiation. Using time course single cell RNA sequencing on XY mouse gonads during sex determination, we identified a single population of somatic progenitor cells prior sex determination. A su...

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Literature Corpus work: 2f5b817b-6707-57c2-a26c-0a4dfe7ca766
DOI: 10.1101/190264

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