Article
Dissecting Mammalian Spermatogenesis Using Spatial Transcriptomics
2020-10-17
Abstract excerpt
<h4>Summary</h4> Single-cell RNA sequencing has revealed extensive molecular diversity in gene programs governing mammalian spermatogenesis but fails to delineate their dynamics in the native context of seminiferous tubules — the spatially-confined functional units of spermatogenesis. Here, we use Slide-seq, a novel spatial transcriptomics technology, to generate a comprehensive spatial atlas that captures the sp...
Topics
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- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Molecular Biology Techniques and Applications
- Prenatal Screening and Diagnostics
- Renal and related cancers
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- 44014abb-c811-5d08-8b36-58ebd331da3a
- DOI
- 10.1101/2020.10.17.343335
