Article

Metabolic profiling studies of tumour cell phenotypes

2011-01-01

Abstract excerpt

Ovarian cancer is a devastating disease affecting millions of women worldwide. Initially successful chemotherapy using platinum-based drugs is often followed by a relapse after which platinum therapy is usually ineffective and prognosis poor. The mechanism by which platinum resistance develops and its reversal to a more sensitive phenotype are of major interest in modern medical oncology, especially for ovarian ca...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 17deb651-400f-505d-833c-2605c60515ab
DOI: 10.25560/6207

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Metabolic profiling studies of tumour cell phenotypesDOI 10.25560/6207Read

NMR Metabolomics of Primary Ovarian Cancer Cells in Comparison to Established Cisplatin-Resistant and -Sensitive Cell LinesSemantic proximity Read

Metabolomic profiling of the effects of melittin and cisplatin on ovarian cancer cells using high resolution mass spectrometrySemantic proximity Read

Metabolic profiling analysis of pharmacodynamic responses to chemotherapy in cancerSemantic proximity Read

Metabolic profiles of cancer cells.Semantic proximity Read

Cancer metabolomicsSemantic proximity Read

Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg EffectSemantic proximity Read

Identification of proteomic and metabolic signatures associated with chemoresistance of human epithelial ovarian cancerSemantic proximity Read

Metformin-induced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells.Semantic proximity Read

(1)H NMR metabolomics analysis of renal cell carcinoma cells: Effect of VHL inactivation on metabolism.Semantic proximity Read

Multi-omic profiling of tyrosine kinase inhibitor-resistant K562 cells suggests metabolic reprogramming to promote cell survivalSemantic proximity Read

The epigenetic response to platinum-induced DNA damage and repairSemantic proximity Read

Metabolic molecular subtyping of ovarian cancer reveals the role of oleic acid-CD36 in facilitating cisplatin resistanceSemantic proximity Read