Article

Patient-specific alterations in blood plasma cfRNA profiles enable accurate classification of cancer patients and controls

2023-05-28

Abstract excerpt

Circulating nucleic acids in blood plasma form an attractive resource to study human health and disease. Here, we applied mRNA capture sequencing of blood plasma cell-free RNA from 266 cancer patients and cancer-free controls (discovery n = 208, 25 cancer types; replication n = 58, 3 types). We observed cancer type-specific as well as pan-cancer alterations in cell-free transcriptomes compared to controls. Differe...

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Identifiers and source

Literature Corpus work: 09441ec8-64db-5fe4-b684-63fa977daf24
DOI: 10.1101/2023.05.24.23290388

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