Article

High dose everolimus promotes a pro-inflammatory phenotype and facilitates the epithelial to mesenchymal transition of primary bronchial epithelial cells isolated from cystic fibrosis patients.

2020-08-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Lung transplantation is still the best therapeutic option for cystic fibrosis (CF) patients, but, unfortunately, immunosuppressive therapies, often employed at high dosages to avoid acute rejection, may induce severe complications. In particular, patients treated with high dose of mammalian target of rapamycin inhibitors (mTOR-Is) may experience lung fibrosis (i...

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Literature Corpus work: 179b2485-ab7c-5e58-9d44-017c341609ed
DOI: 10.21203/rs.3.rs-46751/v1

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High dose everolimus promotes a pro-inflammatory phenotype and facilitates the epithelial to mesenchymal transition of primary bronchial epithelial cells isolated from cystic fibrosis patients.DOI 10.21203/rs.3.rs-46751/v1Read

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