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Development of Inflammatory Models Using Differentiated Human Bronchial Epithelial (HBE) Cells from Cystic Fibrosis Patients for the Pre-Clinical Evaluation of Novel Therapeutic Compounds

2026-07-16

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> There is a persistent need for effective anti-inflammatory therapies for people with cystic fibrosis (pwCF), even in the era of highly effective modulator therapy (hEMT). Although hEMT improves clinical outcomes, this treatment does not fully resolve the chronic airway inflammation that contributes to progressive lung damage and recurrent pulmonary exacerbatio...

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Literature Corpus work
1190cb44-0022-5dc4-8d25-bde041c38b35
DOI
10.21203/rs.3.rs-10282441/v1
Open publication

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Development of Inflammatory Models Using Differentiated Human Bronchial Epithelial (HBE) Cells from Cystic Fibrosis Patients for the Pre-Clinical Evaluation of Novel Therapeutic CompoundsDOI 10.21203/rs.3.rs-10282441/v1
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