Article

The atlas of human cardiac promoters and enhancers reveals an important role for regulatory elements in heart failure

2021-10-28

Abstract excerpt

<title>Abstract</title> <p> A continuous increase in the prevalence of heart failure and the lack of adequate therapy highlight poor understanding of the underlying genetic regulatory mechanisms involved in heart failure pathogenesis. Growing evidence has demonstrated a significant contribution of non-coding genome regulatory elements towards transcriptomic changes in heart disease. Thus, there is a pressing nee...

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Literature Corpus work: 1794afd7-9461-5fb9-97d8-22c33308f086
DOI: 10.21203/rs.3.rs-1010746/v1

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