Article

Systematic analysis of alternative splicing in time course data using Spycone

2022-04-29

Abstract excerpt

During disease progression or organism development, alternative splicing (AS) may lead to isoform switches (IS) that demonstrate similar temporal patterns and reflect the AS co-regulation of such genes. Tools for dynamic process analysis usually neglect AS. Here we propose Spycone ( https://github.com/yollct/spycone ), a splicing-aware framework for time course data analysis. Spycone exploits a novel IS detection...

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Literature Corpus work: 174faa3a-7a53-5132-81f4-5ba7c23f15fa
DOI: 10.1101/2022.04.28.489857

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