Article

Assessing Conservation of Alternative Splicing with Evolutionary Splicing Graphs

2020-11-15

Abstract excerpt

Understanding how protein function has evolved and diversified is of great importance for human genetics and medicine. Here, we tackle the problem of describing the whole transcript variability observed in several species by generalising the definition of splicing graph. We provide a practical solution to building parsimonious evolutionary splicing graphs where each node is a minimal transcript building block def...

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Literature Corpus work: b2ed36a8-9535-51a1-9679-d84455287a56
DOI: 10.1101/2020.11.14.382820

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