Article

AlterNet: Alternative splicing-aware gene regulatory network inference

2025-11-22

Abstract excerpt

Gene regulatory networks (GRNs) help decode biological systems by identifying how genes interact and regulate cellular processes. However, conventional GRN inference methods operate at the gene-level, overlooking transcript-level variability introduced by alternative splicing (AS). In this work, we present AlterNet, the first GRN inference and annotation pipeline which considers isoform of transcription factors as...

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Literature Corpus work: cd0a9c41-afac-5748-bd77-d9bafe210cb2
DOI: 10.1101/2025.11.21.689745

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