Article

Next-Generation Sequencing and Genotype Association Studies Reveal the Association of HLA-DRB3*02:02 With Delayed Hypersensitivity to Penicillins

2021-04-16

Abstract excerpt

<h4>Background: </h4> Nonimmediate (delayed) allergic reactions to penicillins are common and some of them can be life-threatening. The genetic factors influencing these reactions are unknown/poorly known/poorly understood. We assessed the genetic predictors of a delayed penicillin allergy that cover the HLA loci. <h4>Methods:</h4> Using next-generation sequencing (NGS), we genotyped the MHC region in 24 patients...

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Literature Corpus work: 17284fde-3f16-5cdf-8406-3b25670bf080
DOI: 10.22541/au.161857346.60929786/v1

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