Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy.

doi:10.1016/j.ajhg.2020.08.008

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Article

Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy.

American journal of human genetics - 1 Oct 2020

Krebs Kristi, Bovijn Jonas, Zheng Neil, Lepamets Maarja, Censin Jenny C, Jürgenson Tuuli, Särg Dage, Abner Erik, Laisk Triin, Luo Yang, Skotte Line, Geller Frank, Feenstra Bjarke, Wang Wei, Auton Adam, Raychaudhuri Soumya, Esko Tõnu, Metspalu Andres, Laur Sven, Roden Dan M, Wei Wei-Qi, Holmes Michael V, Lindgren Cecilia M, Phillips Elizabeth J, Mägi Reedik, Milani Lili, Fadista João

Abstract excerpt

Hypersensitivity reactions to drugs are often unpredictable and can be life threatening, underscoring a need for understanding their underlying mechanisms and risk factors. The extent to which germline genetic variation influences the risk of commonly reported drug allergies such as penicillin allergy remains largely unknown. We extracted data from the electronic health records of more than 600,000 participants...

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Identifiers

PMID: 32888428
DOI: 10.1016/j.ajhg.2020.08.008
PMCID: PMC7536643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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