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Article

HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping.

The Journal of allergy and clinical immunology - 1 Jan 2015

Guéant Jean-Louis, Romano Antonino, Cornejo-Garcia Jose-Antonio, Oussalah Abderrahim, Chery Celine, Blanca-López Natalia, Guéant-Rodriguez Rosa-Maria, Gaeta Francesco, Rouyer Pierre, Josse Thomas, Canto Gabriella, Carmona F David, Bossini-Castillo Lara, Martin Javier, Laguna Jose-Julio, Fernandez Javier, Feo Francisco, Ostrov David A, Plasencia Pablo C, Mayorga Cristobalina, Torres Maria-Jose, Blanca Miguel

Abstract excerpt

BACKGROUND: Immediate reactions to β-lactams are the most common causes of anaphylactic reactions and can be life-threatening. The few known genetic factors influencing these reactions suggest a link with atopy and inflammation. OBJECTIVE: We performed a fine-mapping genome-wide association study...

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Source

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PMID: 25224099
DOI: 10.1016/j.jaci.2014.07.047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25224099-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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