Article

Neurovascular mitochondrial susceptibility impacts blood-brain barrier function and behavior

2024-02-20

Abstract excerpt

Maintenance of blood-brain barrier (BBB) integrity is critical to optimal brain function, and its impairment has been linked to multiple neurological disorders. A notable feature of the BBB is its elevated mitochondrial content compared to peripheral endothelial cells, although the functional implications of this phenomenon remain unknown. Here we studied BBB mitochondrial function in the context of the 22q11.2 de...

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Literature Corpus work: 17194a98-7992-5c4c-bdbe-5bec5ebb297b
DOI: 10.1101/2024.02.15.580544

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