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Article

Mitochondrial polymorphisms impact outcomes after severe traumatic brain injury.

Journal of neurotrauma - 1 Jan 2014

Conley Yvette P, Okonkwo David O, Deslouches Sandra, Alexander Sheila, Puccio Ava M, Beers Sue R, Ren Dianxu

Abstract excerpt

Patient outcomes are variable following severe traumatic brain injury (TBI); however, the biological underpinnings explaining this variability are unclear. Mitochondrial dysfunction after TBI is well documented, particularly in animal studies. The aim of this study was to investigate the role of mitochondrial polymorphisms on mitochondrial function and patient outcomes out to 1 year after a severe TBI in a human...

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Share to Alleles
Share to Brain Injuries
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Recovery of Function

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Share to Traumatic Brain Injury Research

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Source

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Identifiers

PMID: 23883111
DOI: 10.1089/neu.2013.2855
PMCID: PMC3880110

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