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Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia

2024-06-13

Abstract excerpt

Hypoxia is an important physiological stress causing nerve injuries and several brain diseases. However, the mechanism of brain response to hypoxia remains unclear, thus limiting the development of interventional strategies. This study conducted combined analyses of single-nucleus transcriptome sequencing and extracellular vesicle transcriptome sequencing on hypoxic mouse brains, described cell-cell communication...

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Identifiers and source

Literature Corpus work
e6b4a51e-8d91-5387-8770-c8f48c75726c
DOI
10.1101/2024.06.11.598477
Open publication

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Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxiaDOI 10.1101/2024.06.11.598477
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