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Inhibition of miR-937-3p by targeting SNCB ameliorates rotenone-induced toxicity in SH- SY5Y cells by reducing alpha-synuclein aggregation and apoptosis

2025-06-03

Abstract excerpt

<title>Abstract</title> <p>Parkinson’s disease (PD) is a prevalent neurodegenerative disorder marked by dopaminergic neuronal loss in the substantia nigra and the presence of Lewy bodies formed by alpha-synuclein (α-syn) aggregation. This study was performed to determine whether miR-937-3p inhibited α-syn aggregation and apoptosis in a rotenone (ROT)-induced PD cell model. We examined miR-937-3p target genes thro...

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Literature Corpus work
16db6747-6379-5343-a638-640e2b0711bc
DOI
10.21203/rs.3.rs-6763797/v1
Open publication

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Inhibition of miR-937-3p by targeting SNCB ameliorates rotenone-induced toxicity in SH- SY5Y cells by reducing alpha-synuclein aggregation and apoptosisDOI 10.21203/rs.3.rs-6763797/v1
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