Article

Screening of Botanical Drugs Against Lassa Virus Entry

2020-07-25

Abstract excerpt

Lassa virus (LASV) belongs to the Old World Mammarenavirus genus (family Arenaviridae ) and is classified as a category A biological threat agent. At present, there are no approved drugs or vaccines specific for LASV. In this study, high-throughput screening of a botanical drug library was performed against LASV entry using a pseudotype virus bearing the LASV envelope glycoprotein (GPC). Two hit compounds, berga...

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Identifiers and source

Literature Corpus work: 16c1e411-ce67-5d9f-978c-d05c4d28e0b2
DOI: 10.1101/2020.07.24.220749

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