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Recombinant Pichinde reporter virus as a safe and suitable surrogate for high-throughput antiviral screening against highly pathogenic arenaviruses

2024-12-20

Abstract excerpt

<h4>ABSTRACT</h4> Several arenaviruses, such as the Old World (OW) Lassa virus (LASV) and the New World (NW) Junin virus (JUNV), can cause severe and lethal viral hemorrhagic fevers in humans. Currently, no vaccines or specific antiviral therapies are FDA-approved for treating arenavirus infections. One major challenge for the development of new therapeutic candidates against these highly pathogenic viruses is th...

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Literature Corpus work
8ef1a801-4458-5191-ab74-8256ceddf6e9
DOI
10.1101/2024.12.19.629433
Open publication

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Recombinant Pichinde reporter virus as a safe and suitable surrogate for high-throughput antiviral screening against highly pathogenic arenavirusesDOI 10.1101/2024.12.19.629433
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