Article

Changes in cell morphology and function induced by <i>NRAS</i> Q61R mutation in lymphatic endothelial cells

2023-07-14

Abstract excerpt

Recently, a low-level somatic mutation in NRA S gene (c.182 A > G, Q61R) was identified in the specimens of patients with kaposiform lymphangiomatosis (KLA). However, it is unknown how these low-frequency mutated cells can affect the characterization and surrounding environment of their lesions. To understand the pathogenesis and association of these gene abnormalities, we established NRAS Q61R mutated lymphatic...

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Literature Corpus work: 16950571-e474-5f29-8c52-f0e2c9edf031
DOI: 10.1101/2023.07.14.549027

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