Article

Genomic Landscape of Lymphatic Malformations: A Case Series and Response to the PI3Kα Inhibitor Alpelisib in an N-of-One Clinical Trial

2022-01-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Lymphatic malformations (LMs) often pose treatment challenges due to a large size or a critical location that could lead to disfigurement, and there are no standardized treatment approaches for either refractory or unresectable cases. <h4>Methods</h4> We examined the genomic landscape of a patient cohort of LMs (n=30 cases) that underwent comprehensive genomic profiling (CG...

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Literature Corpus work: 77005525-7e41-5a2c-aa17-efd22fdf9296
DOI: 10.1101/2022.01.03.21267856

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