Article

Exosome TDP-43 Profile in Canine Model of ALS: A Preliminary Study in Developing Surrogate Biomarker

2021-06-18

Abstract excerpt

Blood-based biomarkers are much-needed diagnostic and prognostic tools for ALS. Canine degenerative myelopathy (DM) is recognized animal disease model to study the biology of human ALS. Serum derived exosomes are potential carrier that transport intercellular hormone-like messengers, together with their stability as carrier of proteins and RNA, make them ideal as biomarkers for a variety of diseases and biological...

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Literature Corpus work: 1678e78c-8198-591e-bf23-db30ca6ffc87
DOI: 10.20944/preprints202106.0488.v1

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