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Article

Canine degenerative myelopathy.

The Veterinary clinics of North America. Small animal practice - 1 Sept 2010

Coates Joan R, Wininger Fred A

Abstract excerpt

Canine degenerative myelopathy (DM) is an adult-onset fatal neurodegenerative disease that occurs in many breeds. The initial upper motor neuron spastic paraparesis and general proprioceptive ataxia in the pelvic limbs progress to a flaccid lower motor neuron tetraparesis. Recently, a missense mutation in the superoxide dismutase 1 (SOD1) gene was found to be a risk factor for DM, suggesting that DM is similar to...

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Source

Identifiers

PMID: 20732599
DOI: 10.1016/j.cvsm.2010.05.001

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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