Article

TDP-43 is elevated in plasma neuronal-derived exosomes of patients with Alzheimer's disease

2019-11-27

Abstract excerpt

<title>Abstract</title> <p>Background Recently, TDP-43 has been recognized as a common proteinopathy in the “oldest old” and a neuropathological comorbidity in patients with Alzheimer’s disease (AD). However, since it has a low concentration in cerebrospinal fluid, the presence of TDP-43 in AD is rarely investigated in vivo. Methods Twenty-four patients with amyloid PET confirmed AD and 15 healthy controls (HCs)...

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Literature Corpus work: deeb560b-ebaf-5fd2-b7ef-7aab67c6dcf8
DOI: 10.21203/rs.2.17750/v1

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