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Improved neurocognitive performance in FIV infected cats following treatment with the p75 neurotrophin receptor ligand LM11A-31

2020-06-17

Abstract excerpt

HIV rapidly infects the central nervous system (CNS) and establishes a persistent viral reservoir within microglia, perivascular macrophages and astrocytes. Inefficient control of CNS viral replication by antiretroviral therapy results in chronic inflammation and progressive cognitive decline in up to 50% of infected individuals with no effective treatment options. Neurotrophin based therapies have excellent poten...

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Literature Corpus work
1643c995-be77-5086-9f46-0f23643abc2b
DOI
10.1101/2020.06.17.156596
Open publication

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Improved neurocognitive performance in FIV infected cats following treatment with the p75 neurotrophin receptor ligand LM11A-31DOI 10.1101/2020.06.17.156596
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