Article

Duration of Initial Viremia Modulates Functional Properties of HIV-specific T Cell Receptors

2026-02-18

Abstract excerpt

<title>Abstract</title> <p>Virus-specific CD8+ T cells are crucial in controlling chronic human viral infections such as HIV-1, but the effect of persistent antigen exposure on T cell repertoire formation is not well understood. In this study, we examined epitope-specific CD8+ T cell repertoires in people living with HIV-1, where duration of viremia following hyperacute infection was modulated by the time of init...

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Literature Corpus work: 161415d3-7816-58ec-b52e-72b73aa588de
DOI: 10.21203/rs.3.rs-6668459/v1

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