Article

Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain

2023-03-06

Abstract excerpt

Genomic regulatory elements active in the developing human brain are notably enriched in genetic risk for neuropsychiatric disorders, including autism spectrum disorder (ASD), schizophrenia, and bipolar disorder. However, prioritizing the specific risk genes and candidate molecular mechanisms underlying these genetic enrichments has been hindered by the lack of a single unified large-scale gene regulatory atlas of...

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Literature Corpus work: 1602ebd1-f858-50f3-afcf-92479c025a58
DOI: 10.1101/2023.03.03.23286706

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