Article

Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution

2025-09-16

Abstract excerpt

Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle that enables homothallism, i.e., mating between mitotic descendants of the same haploid cell. Yet heterothallic isolates that have lost this ability are found across diverse niches, indicating that this trait is poly...

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Literature Corpus work: 15ef5b61-6948-5498-a755-302d8c3a75ce
DOI: 10.1101/2025.09.12.675800

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