Article
Extensive Recombination of a Yeast Diploid Hybrid through Meiotic Reversion.
PLoS genetics - 1 Feb 2016
Laureau Raphaëlle, Loeillet Sophie, Salinas Francisco, Bergström Anders, Legoix-Né Patricia, Liti Gianni, Nicolas Alain
Abstract excerpt
In somatic cells, recombination between the homologous chromosomes followed by equational segregation leads to loss of heterozygosity events (LOH), allowing the expression of recessive alleles and the production of novel allele combinations that are potentially beneficial upon Darwinian selection. However, inter-homolog recombination in somatic cells is rare, thus reducing potential genetic variation. Here, we...
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