Article

Novel sex-biased outcomes in neuroblastoma are associated with distinct gene expression and chromosomal loss patterns

2024-06-17

Abstract excerpt

The worst patient outcomes in neuroblastoma are driven by high-risk disease 1,2 , which is divided into similarly sized MYCN amplified and MYCN non-amplified patient subgroups 3 . Male patients have been reported to have slightly worse outcomes than females in all-patient analyses of multiple studies 3,4 . However, we show here that in MYCN non- amplified high-risk and stage 4s low-risk disease, female patie...

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Literature Corpus work: 1593ef55-5930-5ca2-b442-45bec1b473ae
DOI: 10.1101/2024.06.14.599094

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